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IJAR.2018.335

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Type of Article:  Original Research

Volume 6; Issue 4.1 (October 2018)

Page No.: 5754-5759

DOI: https://dx.doi.org/10.16965/ijar.2018.335

RISK OF DOWN SYNDROME IN ELDERLY MOTHERS: A RETROSPECTIVE STUDY IN TUMKUR

Vidya H.K 1, Krishnaveni Sharath *2, Asha K.R 3.

1 Assistant Professor, Department of Anatomy, Sridevi Medical college & Hospital, Tumkur, Karnataka, India.

*2 Assistant Professor, Department of Anatomy, SreeBalaji Medical College & Hospital, BIHER, Chrompet, Chennai, Tami Nadu, India.

3 Assistant Professor, Department of Anatomy, Sri Siddhartha Medical College &Hospital, Tumkur, Karnataka, India.

Corresponding author: Dr Krishnaveni Sharath, Assistant Professor, Department of Anatomy, Sree Balaji Medical College, BIHER,  Chrompet, Chennai, Tamil Nadu, India. E-Mail: doc_krisu@yahoo.co.in Phone: 9061745504

ABSTRACT:

Background: Down syndrome being the most common chromosomal disorder is researched extensively. The only etiology that is well established is increased maternal age. In the developing countries, the incidence of Down syndrome is increasing in younger mother.

Method: 75 cases of Down syndrome children and age matched 75 children without known congenital abnormalities were taken for this study. The parental age was noted and statistical analysis was done to correlate the maternal age withy DS.

Result: Only 26.4% of DS children were born in mothers aged above 35. There was a decrease in number of children born in aged mothers of both group, but there was no much difference in the groups.

Conclusion: Maternal age is not only the risk factor for occurrence of DS. There is generally a tendency of early pregnancy in India, which leads to increase in number of DS children being born to mothers below 35.

Key words: Down syndrome, Maternal age.

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Cite this article: Vidya H.K, Krishnaveni Sharath, Asha K.R. RISK OF DOWN SYNDROME IN ELDERLY MOTHERS: A RETROSPECTIVE STUDY IN TUMKUR. Int J Anat Res 2018;6(4.1):5754-5759. DOI: 10.16965/ijar.2018.335