IJAR.2017.137

Type of Article:  Original Research

Volume 5; Issue 1 (March 2017)

Page No.: 3665-3670

DOI: https://dx.doi.org/10.16965/ijar.2017.137

A STUDY ON THE THICKNESS OF LIGAMENTUM FLAVUM IN ASYMPTOMATIC PERSONS AND PATIENTS WITH LOW BACK PAIN AND ITS VARIATION WITH GENDER IN EASTERN INDIAN POPULATION- AS MEASURED USING MRI

Panchali Som 1, Rajarshi Roy *2, Sumit Datta 3, Asis Kumar Ghosal 4, Ananda Kisor Pal 5, Shankhadeep Sarkar 6.

1 Assistant Professor, Department of Anatomy, Mata Gujri Memorial Medical College, Kishanganj, Purabbali, Dinajpur Road, Kishanganj, Bihar, India.

*2 Assistant Professor, Department of Anatomy, Jagannath Gupta Institute of Medical Science & Hospital, Budge Budge, Kolkata, West Bengal, India.

3 Consultant Radiologist, AMRI Hospital, Kolkata, West Bengal, India.

4 Professor and Head of the Department, Department of Anatomy, Institute of Post Graduate Medical Education & Research, Kolkata, West Bengal, India.

5 Professor and Head of the Department, Department of Orthopedics, Institute of Post Graduate Medical Education & Research, Kolkata, West Bengal, India.

6 Post Graduate Trainee, Department Respiratory Medicine, Medical college, Kolkata, West Bengal, India.

Corresponding Author: Assistant Professor, Department of Anatomy, Jagannath Gupta Institute of Medical Science & Hospital, Budge Budge, Kolkata, West Bengal, India. Mobile number: 09433110980 E-Mail: rajarshi.bubai@gmail.com

ABSTRACT

Background: Lumber spinal canal stenosis is common spinal disorder in elderly patients causing low back pain. Ligamentum Flavum (LF) covers most of the postero-lateral part of spinal canal, hypertrophy of which considered an important causative factor in development of lumbar spinal canal stenosis which significantly contributes to low back pain and sciatica.

Materials and Methods: To measure the thickness of LF in in lumbar region at L1-L2, L2-L3, L3-L4, L4-L5, L5-S1 level on MRI a cross sectional MRI study of lumbar spine was carried out between the age group of 20-50 yrs in IPGMER and SSKM hospital, Kolkata. The study population comprised of two groups with a total 120 population of which first group comprised of patients with low back pain (LBP) (n=60), second group was control groups, persons without low back pain (n=60). T1 weighted magnetic resonance images of lumbar segments were taken and thickness of LF was measured on both right and left side in all lumbar segments.

Results: The mean thickness of LF in lumbar segment in LBP group was 3.47mm which was significantly thicker than control group measuring 2.63 mm.

Conclusion:  Patients with low back pain had significantly thicker LF in lumbar segments when compared to asymptomatic persons in both the sides which may be a contributing factor for LBP.

Key words: Ligamenta flava, Lumbar spine, Low back pain.

REFERENCES

  1. Beamer YB, Garner JT, Shelden CH. Hypertro-phied ligamentum flavum. Arch Surg 1973;106:289–292.
  2. Baily P, Casamajor L. Osteo-arthritis of the spine as a cause of compression of the spinal cord and its roots: with report of five cases. J Nerv Ment Dis 1911;38:588–609.
  3. Park JB, Chang H, Lee JK. Quantitative analysis of transforming growth factor-beta1 in ligamentum flavum of lumbar spinal stenosis and disc herniation. Spine 2001;26:E492–495.
  4. Towne EB, Reichert FL. Compression of the lumbosacral roots of the spinal cord by thickened ligamenta flava. Ann Surg 1931;94:327–336.
  5. Ulrich CG, Binet EF, Sanechi MG ,Kieffer SA.Quantitative assessment of the spinal canal by computed tomography.Radiology 1980 Jan;134(1):137–143.
  6. Okuda T, Baba I, Fujimoto Y, et al. The pathology of ligamentum flavum in degenerative lumbar spine. Spine 2004;29:1689–1697.
  7. Yoshida M, Shima K, Taniguchi Y, et al. Hypertrophied ligamentum flavum in lumbar spinal canal stenosis. Spine 1992;17:1353–1360.
  8. Elsberg CA. Experience in spinal surgery. Surg Gynecol Obstet 1913;16:117.
  9. Sortland O, Magnaes B, Hauge T. Functional myolography with metrizamide in the diagnosis of lumbar spinal stenosis. Acta Radiol Suppl 1977;355:42–54.
  10. Teng P, Papatheodorou C. Myelographic findings in spondylosis of the lumbar spine. Br J Radiol 1963;36:122–128.
  11. Avrahami E, Wigler I, Stern D, et al. Computed tomographic (CT) demonstration of the ligament flava of the lumbosacral spine associated with protrusion of the intervertebral disc. Spine 1990;15:21–23.
  12. Kirkaldy-Willis WH, Hithoff KB, Tchang S, et al. Lumbar spondylosis and stenosis: correlation of pathologic anatomy with high resolution computed tomography scanning. In: Post JD, ed. Computed Tomography of the Spine. Baltimore, MD: Williams & Wilkins;1984:546–549.
  13. Olszewski AD, Yaszemski MJ, White AA 3rd. The anatomy of the human lumbar ligamentum flavum. New observations and their surgical importance.Spine (Phila Pa 1976) 1996 Oct 15;21(20):230712.
  14. Chokshi FH, Quencer RM, Smoker WR. The “thickened” ligamentum flavum: is it bucklingor enlargement? AJNR Am J Neuroradiol. 2010; 31(10):1813-1816.
  15. Safak AA, Is M, Sevinc O, Barut C, Eryoruk N, Erdogmus B, Dosoglu M:The thickness of the ligamentum flavum in relation to age and gender. ClinAnat 2010;23(1):79-83.
  16. Fukuyama S, Nakamura T, Ikeda T, Takagi K. The effect of mechanical stress on hypertrophy of the lumbar ligamentum flavum. J Spinal Disord 1995;8:126-130.
  17. Abbas, K. Hamoud, Y. M. Masharawi et al. Ligamentum flavum thickness in normal and stenotic lumbar spines. Spine 2010; vol.35(12):1225–1230.
  18. Altinkaya N, Yildirim T, Demir S, et al. Factors Associated With the Thickness of the Ligamentum Flavum: Is Ligamentum Flavum Thickening Due to Hypertrophy or Buckling? SPINE 2001;36(16):1093–1097.
  19. Kolte V S, Khambatta S et al. Thickness of the Ligamentum Flavum: Correlation with Age and Its Asymmetry–An Magnetic Resonance Imaging Study. Asian Spine J 2015;9(2):245-253.
  20. Grenier N, Kressel HY, Schiebler ML, Grossman RI, Dalinka MK. Normal and degenerative posterior spinal structures: MR imaging. Radiology 1987 Nov;165(2):517-525.
  21. Andrew J, Haig et al .The Ligamentum Flavum at L4L5: Relationship with anthropometric factors and clinical findings in older persons with and without spinal disorders: The American Academy of Physical Medicine and Rehabilitation 2012;4:23-29.
  22. Haveen A. Akreyi, Hayam Y, Awdish  et al. Assessment of ligamentum flavum thickness correlation with demographic variables and disc degeration in Erbil governorate population sample :Zanco J. Med. Sci. 2012;16(2):145-150.

Cite this article: Panchali Som, Rajarshi Roy, Sumit Datta, Asis Kumar Ghosal, Ananda Kisor Pal, Shankhadeep Sarkar. A STUDY ON THE THICKNESS OF LIGAMENTUM FLAVUM IN ASYMPTOMATIC PERSONS AND PATIENTS WITH LOW BACK PAIN AND ITS VARIATION WITH GENDER IN EASTERN INDIAN POPULATION- AS MEASURED USING MRI. Int J Anat Res 2017;5(1):3665-3670. DOI: 10.16965/ijar.2017.137