IJAR.2018.142

Type of Article:  Original Research

Volume 6; Issue 2.1 (April 2018)

Page No.: 5149-5155

DOI: https://dx.doi.org/10.16965/ijar.2018.142

A COMPARATIVE STUDY OF MACROSCOPIC MORPHOLOGY OF PLACENTA AMONG NORMAL AND COMPLICATED PREGNANCIES

Muthuprasad Puthuraj 1, Sumathi Shanmugam *2.

1 Senior Assistant Professor, KAPV Government Medical College, Thiruchirapalli.

*2 Senior Assistant Professor, Thanjavur Medical College, Thanjavur.

Address for Correspondence: Dr.Sumathi Shanmugam, MS, 59, First Street, North Natarajapuram, Thanjavur-613004, Tamil Nadu, India. E-Mail: tnjsumathi@gmail.com

ABSTRACT:

Background: The placenta being a foetal organ, undergoes the same stress and strain to which the foetus is exposed. Common yet life threatening complications of Pregnancy like Gestational Diabetes, Hypertension, Anaemia and Intra uterine growth retardation result in both macroscopic as well as microscopic changes in the placenta. Hence study of the placenta will give a valuable insight in cases of adverse foetal outcome.

Materials and Methods: The present study was conducted on  a total of two hundred and ninety two  freshly delivered placentae with umbilical cord obtained from the labour rooms and operating theatres of the Department of Obstetrics & Gynaecology. Exclusion criteria was multiple pregnancy. Inclusion criteria’s were  normal uncomplicated primigravida and multigravida  and pathological factors complicating pregnancy like Anaemia, Gestational Diabetes mellitus, Pregnancy induced Hypertension and prematurity. The 292 placentae were divided into four categories according to the risk factors and clinical diagnosis of pregnant women namely normal patients(147), patients with Pregnancy induced hypertension(15), Gestational Diabetes mellitus(30) , anaemia(65) and preterm(35).

Results: The circular type of placenta is the common shape of placenta. The diameter of the placenta is increased in anaemia ,gestational diabetes and decreased in prematurity. The weight of the placenta is increased in gestational diabetes mellitus, anaemia and decreased in prematurity. The number of maternal cotyledons is decreased in prematurity and increased in gestational diabetes  mellitus. The eccentric type of cord attachment is the most common type in complicated pregnancies.

Conclusion: The diagnosis of such risk factors in pregnancies during antenatal period and early intervention will improve the perinatal outcome.

Key words: Placenta, Macroscopic Morphology, Complicated Pregnancies.

REFERENCES

  1. Udainia A and Jain ML. Morphological study of placenta in pregnancy induced hypertension with its clinical relevance. J Anat Soc India, 2001; 50(1): 24-27.
  2. Batnagar S.M,Kotari M.L, Lopa A. Mahata. Essential of Human Embryology .3nd edition, Orient Longman, Hyderabad,2000;47-52..
  3. Vascular Anatomy of Human Placenta. Am.J.Obstet.Gynec, 1962;84:1543-1567.
  4. Susan Standring. Implantation and placentation. In:Gray`s Anatomy- The Anatomical basis of clinical practice, 40th ed,Churchill Livingstone,Spain,2008;176-180.
  5. Keith L Moore and Persaud T.V.N. Placenta and membranes.In:The Developing Human- Clinically oriented Embryology. 7th ed,Saunders, Philadelphia,2005;120-131.
  6. Manik Sirpurkar, Vaibhav Prakash Anjankar. Study of correlation between placental morphology and adverse perinatal outcome in different conditions affecting pregnancy. Int J Reprod Contracept Obstet Gynecol. 2015;4(4):1165-1168.
  7. K,Kaufmann.P, Baergen R. Pathology of the Human Placenta. 5th edition, Vol.Chapter.7 Architecture of normal villous trees, New York. Springer Verlag.2006:121-159.
  8. Carolyn M. Salafia, Michael Yampolsky, Dawn P Misra, Oleksander Shlakhter, Danielle Haas, Barbara Eucker, and John Thorp. Placental surface shape, function, and effects of maternal and fetal vascular pathology. Placenta. 2010;31(11):958–962.
  9. Morphology and Histology study of Placenta. 1986;75-78.
  10. Gunapriya R. The morphology , morphometric study of placenta and umbilical cord with vascular pattern and clinical correlation. 2001;28-43.
  11. Gunapriya Raghunath, Vijayalakshmi and Varsha Shenoy. A study on morphology and morphometry of human placenta and its clinical relevance in a population in Tamilnadu. JCDR, 2011;5(2):282-286.
  12. A.A: The effect of congenital abnormalities of the umbilical cord and placenta on the new born and mother: A survey on 5676 consecutive deliveries. J. Obs.Gynaecol.Brit Emp.58:456-459
  13. Shanklin D.R. The Human Placenta: a clinicopathological study. J obst Gynec,1958;13:325-336.
  14. Eastman N.J. and Hellmann L.M: Williams obstetrics,12th ed , Appleton,Newyork,.1971;612-638.
  15. Uyanwah, Akpono P.O and Fox .H ; The clinical significance of marginal or velamentous insertion of cord . Brit.J. Obstet Gynaecol, 1977;84:941-943
  16. Scott .J.S. Placenta extrachorialis (Placenta marginata and Placenta circumvalata);-A factor in Antepartum Heamorrhage. J. Obst. Gynaecol Brit. Emp,1960;67(6):904-918.
  17. J.D , Hamilton W.J. Development and structure of the human placeta from the end of the 3rd month of gestation..J obs Gynaecol Bri commonwealth,1967;74(2):161-226.
  18. Sharmila Bhanu P, Devi Sankar K, Sujatha Kiran, Subhadra Devi V. Gross morphological study of gestational diabetes mellitus placenta from south Indian mothers compared with control placenta. Int J Anat Res, 2017;5(1):3521-3526.
  19. Majumdar S, Dasgupta H, Bhattacharya K and Bhattacharya A. A study of placenta in normal and hypertensive pregnancies. J Anat Soc India, 2005;54(2):34-38.
  20. Wong T.C , Lartour J.P.A. Microscopic measurement of the placental components in an attempt to assess the malnourished newborn infants Am J Obs.Gynaec, 1966; 9:942.
  21. Kucuz, M, Doymary F . Placental weight and Placental weight to birth weight ratio are increased in diet and exercise treated gestational diabetes mellitus subjects but not in one abnormal value on 100gram oral glucose tolerance test. J. Diabetes complication, 2008;
  22. Gupta S.P , Bahl L, Dikshit S.K. A study of Placenta in relation to birth weight and gestational age . Indian J Paediatrics,1972;39(9):281-285.
  23. William P.L., Wendell Smith C.P.,Treadgold. S Basic Human Embryology , 2nd edition ; Lippincott Philadelphia, 1969;
  24. Leslie B Developmental Anatomy,7th ed, WB.Saunders, Philadelphia1974;138.
  25. Richard S Snell .Structure of placenta.In: Clinica lAnatomy by regions,9th ed, Lippincott Williams & Wilkins, 2008;293-294.
  26. Thomson AM, Billewicz WZ and Hytten FE. The weight of the placenta in relation to birth weight. J Obst and Gyaecol Br Commonwealth. 1969;76(10):865-872.
  27. Gauster M, Desoye G, Tötsch M, Hiden U.The placenta and gestational diabetes mellitus. Curr Diab Rep, 2012;12:16-23.
  28. Fox H. The morphological basis of placental insufficiency.J Obs  Gynaecol India. 1975;25:441–450.
  29. Mayhew TM, Sisley I. Quantitative studies on the villi, trophoblast and intervillous pores of placentae from women with well-controlled diabetes mellitus. Placenta,1998;19:371-377.
  30. Pankaj Saini, Jai Prakash Pankaj, Anjali Jain and Gyan Chand Agarwal. Effect of gestational diabetes mellitus on gross morphology of placenta: a comparative study. Int J Anat Res 2015;3(1):889-94.
  31. Saha S, Biswas S, Mitra D, Adhikari A and Saha C. Histologic and morphometric study of human placenta in gestational diabetesmellitus. Ital J Anat Embryol. 2014;119(1):1-9.
  32. Ashfaq M, Janjua MZ and Channa MA. Effect of gestational diabetes and maternal hypertension on gross morphology of placenta. J Ayub Med Coll Abbottabad. 2005;17(1):44.
  33. Sengupta K. Shamim A, Khandekar AR and Mahamuda B. Morphological changes of placenta in preeclampsia. Bangladesh Journal of Anatomy. 2009;7(1):49-54.
  34. Anjankar V, et al. Placental Morphometry in Toxaemia of Pregnancy. Scholars Journal of Applied Medical Sciences. 2014;2(1B):205-8.
  35. Londhe Pradeep S, Mane Abhay B. Morphometric study of placenta and its correlation in normal and hypertensive pregnancies. International Journal of Pharma and Biosciences, 2011;4(2):429-437.
  36. Sirpurkar M, Anjankar VP. Study of correlation between placental morphology and adverse perinatal outcome in different conditions affecting pregnancy. Int J Reprod Contracept Obstet Gynecol ,2015;4:1165-1168.
  37. Suneeta Singh, Arpitha Pemmaraju, Devendra Nema. Comparison of Placental Histopathology in IUGR and Normal Term Infants: A Cross-Sectional Study. Journal of Dental and Medical Sciences, 2017;16(1):36-40.

Cite this article: Muthuprasad Puthuraj, Sumathi Shanmugam. A COMPARATIVE STUDY OF MACROSCOPIC MORPHOLOGY OF PLACENTA AMONG NORMAL AND COMPLICATED PREGNANCIES. Int J Anat Res 2018;6(2.1):5149-5155. DOI: 10.16965/ijar.2018.142