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IJAR.2019.221

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Type of Article:  Original Research

Volume 7; Issue 3.1 (July 2019)

Page No.: 6775-6779

DOI: https://dx.doi.org/10.16965/ijar.2019.221

HISTOMORPHOMETRIC ASSESSMENT OF WHARTON’S JELLY AREA IN NORMAL AND PRE-ECLAMPTIC PREGNANCIES AND ITS CORRELATION WITH PLACENTAL WEIGHT

Ankit Jain 1, Prateek Shrivastava *2, Rashmi Jain 3.

1 M.S., Assistant Professor, Department of Anatomy, Shyam Shah Medical College, Rewa (M.P.), India.

*2 Resident, Department of Anatomy, Mahatma Gandhi Memorial Medical College, Indore (M.P.), India.

3 M.D., Assistant Professor, Department of Pathology, Shyam Shah Medical College, Rewa (M.P.), India

Corresponding author: Dr. Prateek Shrivastava, Resident, Department of Anatomy, Mahatma Gandhi Memorial Medical College, Indore (M.P.), India. Telephone: +91 9827570908. E-Mail: ankitjain6285@gmail.com

ABSTRACT:

Introduction: Fetal capability to grow in utero depends on placental development and function. The goal of this study was to appraise the effects of hypertension on placental weight and Wharton’s jelly area (WJA); and correlate them in normal and pre-eclamptic pregnancies.

Material and Methods: Eighty placentae along with umbilical cord divided into forty each of normotensive and pre-eclamptic pregnancies were studied. The cross-sectional area of the umbilical cord and vessels area was measured with the help of vernier scale and ocular micrometer respectively. WJA was calculated by deduction of the vascular area from the umbilical cord area. Placental weight was recorded by using a weighing machine and correlated with the WJA.

Results: In the present study, mean placental weight was 445.45 ± 40.31 grams and WJA was 35.28 ± 8.42 mm2 in the normal group. Whereas, in the pre-eclamptic group, mean placental weight was 408.95 ± 47.15 grams and WJA was 29.04 ± 8.09 mm2. Mean placental weight and WJA was significantly lower in the pre-eclamptic group. A significant positive correlation was found between WJA and placental weight (r = 0.710, p<0.0001) in normal group and (r = 0.764, p<0.0001) in pre-eclamptic group.

Conclusion: Pre-eclampsia is associated with reducing placental weight and WJA. Low WJA may hamper the fetal growth. The current study shows a strong positive correlation between WJA and placental weight. So, the awareness of this correlation will be helpful in the early observation of placental insufficiencies and provide sufficient information to take additional care in such conditions.

Key words: Wharton’s jelly, Placental weight, Pre-eclampsia, Umbilical cord.

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Cite this article: Ankit Jain, Prateek Shrivastava, Rashmi Jain. HISTOMORPHOMETRIC ASSESSMENT OF WHARTON’S JELLY AREA IN NORMAL AND PRE-ECLAMPTIC PREGNANCIES AND ITS CORRELATION WITH PLACENTAL WEIGHT. Int J Anat Res 2019;7(3.1):6775-6779. DOI: 10.16965/ijar.2019.221