IJAR.2023.142
Type of Article: Original Research
Volume 12; Issue 1 (March 2024)
Page No.: 8800-8807
DOI: https://dx.doi.org/10.16965/ijar.2023.142
Diffusion Weighted Imaging and Grading of Brain Tumours
Manah Chandra Changmai *1a,1b, Mohammed Faruque Reza 2, Kastury Gohain 3.
*1a Lecturer, Centre for Anatomy and Human Identification, University of Dundee, Dundee, United Kingdom, b Universiti Sains, Malaysia. ORCiD: 0000-0001-6440-2752
2 Senior Lecturer, Department of Neuroscience, School of Medicine, Universiti Sains Malaysia, Kubang kerian, Kelantan, Malaysia. ORCiD: 0000-0002-0302-6623
3 Lecturer, School of Business, University of Dundee, Dundee, United Kingdom.ORCiD: 0000-0002-5190-8620
Corresponding Author: Dr Manah Chandra Changmai, PhD Graduate Universiti Sains Malaysia, Malaysia. Lecturer, Centre for Anatomy and Human Identification, University of Dundee, Dundee, United Kingdom. E-Mail: manahchangmai@gmail.com
ABSTRACT
Background: Most prevalent primary cerebral tumours are meningiomas. The other frequent intracranial tumours are pituitary adenomas, which are benign, and gliomas, which are intra-axial brain tumours. The objective of this study is to understand the importance of DW MRI imaging with standard b-value in differentiating presurgical grading of the brain tumour.
Design: A total of 24 DWI patients, including 12 meningiomas, 8 gliomas, and 4 pituitary adenomas, were included in this retrospective analysis.
Method: The Stejskal-Tanner equation is used to analyse the ADCmean, ADCmin, and ADCmax values from the healthy and tumour core that are obtained out from area of interest (ROI).
Result: The ADCmean value of Gliomas ranges from 0.09 x 10-3 mm2s-1 to 0.99 x 10-3 mm2s-1 with a median value of 0.25 x 10-3 mm2s-1. ADCmean value 1.82 x 10-3 mm2/s (sensitivity: 67%. Specificity: 81.8%) and 0.94 x 10-3 mm2/s (sensitivity: 75%. specificity: 81.3%) can discriminate grade II –IV meningioma from grade II-IV glioma.
Conclusion: The ADC and its threshold levels offer crucial details on the grades, consistency, and characterization of tumour, aiding accurate diagnosis and therapy.
Keywords: Brain tumour, Imaging, MRI, DWI, ADC, b-value.
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