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Type of Article : Original Article

Year: 2014 | Volume 2 | Issue 4 | Page No. 806-809

Date of Publication: 31-12-2014

DOI: 10.16965/ijar.2014.553

EFFECTS OF FRUITS OF BARRINGTONIA RACEMOSA LINN. ON HUMAN POLYMORPHONUCLEAR CELL

Sudha Patil ¹, Mahesh Ramu Patil ², Prabhakar Patil *³, Rohit Dixit ⁴, Rajesh C Sharma ⁵.

^1,*3,4,5 Navodaya Medical College Raichur, Karnataka, India.
² R.C. Patel College of Pharmacy, Shirpur, Dhule, Maharashtra, India.

Address: Dr. Prabhakar Patil, Navodaya Medical College, Raichur, Karnataka, India. Mobile No. +919900346851.
E-Mail: drprpatil2006@gmail.com

Abstract

The objective of present study was to investigate Petroleum ether, ethyl acetate and hydroalcoholic extracts of B. racemosa fruits in vitro on human polymorphonuclear (PMN) cells to screen their effects on phagocytosis and chemotaxis. Ethyl acetate extract of B. racemosa fruits was found to be a stimulant of PMN cell phagocytosis of Nitroblue tetrazolium (NBT) dye and candida albicans. It also stimulated intracellur killing capacity of PMN cells. It was further found to increase the chemotaxis of human PMN cells. While, petroleum ether extract and hydroalcoholic extract were lesser active as far as these activities are concerned.
KEYWORDS: Barringtonia racemosa, Phagocytosis, Chemotaxis, Polymorphonuclear cells.

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Sudha Patil, Mahesh Ramu Patil, Prabhakar Patil, Rohit Dixit, Rajesh C Sharma. EFFECTS OF FRUITS OF BARRINGTONIA RACEMOSA LINN. ON HUMAN POLYMORPHONUCLEAR CELL. Int J Anat Res 2014;2(4):806-809. DOI: 10.16965/ijar.2014.553