International Journal of Anatomy and Research

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Type of Article : Original Research

Year: 2015 | Volume 3 | Issue 3 | Page No. 1259-1266

Date of Publication: 31-08-2015



Asra Anjum *1, D.Suseelamma 2, S.Saritha 3, T.V. Ramani 4D.NagaJyothi 5.

*1 Lecturer of Anatomy, KAMS&RC, Hyderabad, Telangana, India.
2 Professor and Head, Dept of Anatomy, Mamatha Medical college, Khammam, Telangana, India.
3 Professor and Head, Dept of Anatomy, KAMS&RC, Hyderabad, Telangana, India.
4 Asst Prof, Dept of Anatomy, KAMS&RC, Hyderabad, Telangana, India.
5 Asst Prof, Dept of Anatomy, KAMS&RC, Hyderabad, Telangana, India.

Address: Mrs. Asra Anjum, Lecturer of Anatomy, KAMS&RC, Hyderabad, Telangana, India.


Introduction: The word “Placenta” is a Latin word and the Greek equivalent word is “Plakons” which means “Flat cake on a plate”. The placenta is a complex multifunctional organ. It provides nutrition, gas exchange, waste removal, endocrine function and immune support. Placenta is a special circulating system to the developing foetus. Being an organ of vital importance for continuation of pregnancy and foetal nutrition it has evolved great interest among the anatomists, embryologists, pathologists and obstetricians.
Materials and Methods: The study was done in 50 placentae which were collected from the department of Obstetrics and Gynaecology in collaboration with the department of Anatomy, Kamineni Institute of Medical Sciences, Narketpally, Nalgonda, Telangana, during the period of 2 years. The morphological variations of placenta, the size, shape, weight and attachment of umbilical cord with its blood vessels were observed, recorded and photographed. The prime objective of the study is to compare and evaluate the morphological alterations of placenta and umbilical cord in pregnancy.
Results and Conclusion: In the current study, the majority of the placentae showed round shape, few placentae with oval and irregular and with an accessory lobe in single placenta.  The current study also includes variations in insertion of umbilical cords was eccentric in majority, central,  marginal and velamentous in a few. Pregnancy induced hypertension significantly affects the placenta by reducing weight and it does not have any significant effect on the shape of placenta, umbilical cord insertion and number of cotyledons on maternal surface. The placenta is the most accurate record of the infants prenatal experience.
KEY WORDS: Placenta, Umbilical cord, morphometry, variations, umbilical vessels.


  1. Yetter, J. F. Examination of the placenta, American Academy of Family Physicians. 1998;57(5);1045-1054.
  2. Kaplan, L.G. Forensic aspect of the placenta. Prospect of paediatric pathology, 1995;19:20-42.
  3. Benirshke K. The Placenta: How to examine it and what you can learn. Contempt Obst & Gynaecol 1981;17:117-19.
  4. Borton, C.(2006) Placenta and Placental Problems. Patient Plus, 20:159.
  5. Susan Standring, Thomas Ind. Gray’s Anatomy – The Anatomical Basis of Clinical Practice. Implantation, Placentation, Pregnancy and Parturition. 39th Ed, London: Churchill Livingstone;2005. Pg: 1341-1348.
  6. Van den Broek, N., Ntonya, C., Kayira, E., White, S. and Neilson, J. P. Preterm birth in rural Malawi: high incidence in ultrasound-dated population. Human Reproduction, 2005;20:3235-3237.
  7. T.W.Sadler. Langman’s Medical Embryology. The fetus and Placenta. 11th Ed. Wolters Kluwer (India) Pvt Ltd,2011:pg:91-111.
  8. A.K. Datta, Essentials of Human Embryology. The placenta. 5th Ed, Current Books International Publishers; 2005; pg-59.
  9. Manop Janthanaphan MD, Ounjai Kor-anantakul MD, AlanGeater PhD. Placental weight and its ratio to birth weight in normal pregnancy at Songkhlanagarind Hospital. J Med Assoc Thai. 2006; 89(2):130-137.
  10. Cross JC. The genetics of pre-eclampsia: a feto-placental or maternal problems? Cli genetics, 64, 2000, 96-103.
  11. Machin, G. A., Ackerman, J. and Gilbert-Barness, E. Abnormal umbilical cord coiling is associated with adverse perinatal outcomes. Paediatric and Developmental Pathology, 2000;3:465-471.
  12. Gunapriya Raghunath, Vijayalakshmi, Varsha Shenoy. Clinically relevant morphology and morphometry of Placenta. Journal of Clinical and Diagnostic Research. 2011 Apr;5(2):282-286.
  13. Peter Kwabena Appiah. Relationship between the morphology of placenta, Umbilical cord and Perinatal Outcome,2009.
  14. Sinan Karadeniz R., Necdet Kocabiyek, Cenk Kilic, Bulent Yakin, M- Metin Altay, Hasan Ozan: Morphometry of Human Placentas: a comparision of placental parameters. Cilt 2007;49(3):153-156.
  15. Benirschke K. Obstetrically important lesions of the umbilical cord. J Reprod Med 1994; 39:262-272.
  16. Leung AK, Robson WL. Single umbilical artery. A report of 159 cases. Am J Dis Child 1989;143:108-111.
  17. Rodriguez MA four-vessel umbilical cord without congenital abnormalities. South Med J 1984 Apr;77(4):539
  18. Painter D, Russell P. Four-vessel umbilical cord without congenital anomalies. Obstet Gynecol 1977 Oct;50(4): 505-7.
  19. Meyer WW, Lind J, Moinian M. An accessory fourth vessel of the umbilical cord. A preliminary study. Am J Obstet Gynecol. 1969 Dec 1; 105(7): 1063-8.
  20. Cunningham FG, Gant NF, Leveno KJ, Gilstron LC, Hauth JC, Wenstrom KD. Abnormalities of the umbilical cord. Williams Obstetrics. 21st ed. New York: McGraw-Hill Medical Publishing Division, 2001:831-835.
  21. Gupta, S., Faradi, M. M. A and Krishnan, J. Umbilical cord Index. Journal of Gynecology, India, 2006;56(4):315-319.
  22. Lacro RV, Jones KL, Benirschke K. The umbilical cord twist: origin, direction, and elevance. Am J Obstet Gynecol 1987;157: 833-838.


Asra Anjum, D.Suseelamma, S.Saritha, T.V. Ramani, D.NagaJyothi. STUDY OF MORPHOLOGICAL VARIATIONS OF 50 PLACENTAE WITH UMBILICAL CORDS AND ITS DEVELOPMENTAL RELEVANCE. Int J Anat Res 2015;3(3):1259-1266. DOI: 10.16965/ijar.2015.198




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