EFFICACY OF MCKENZIE PROTOCOL ON NON-SPECIFIC NECK PAIN Reham Hussein Diab * 1 , Rania Hakem Hamed 2 ,  Ibrahem Mustafa Mustafa 3 . * 1,3 Department of Basic Science, Faculty of Physical Therapy, Cairo University.   2 Researcher (M.SC candidate) at the department of basic Science, Faculty of Physical Therapy ,Cairo university. Address:     Dr.     Reham     Hussein     Diab,     Department     of     Basic     Science,     Faculty     of     Physical     Therapy,     Cairo     University.     E-Mail: reham.diab@yahoo.com ABSTRACT Background:   Neck   pain   is   the   most   common   and   painful   musculoskeletal   condition   which   has   a   great   socioeconomic   burden   on   both patients   and   society.   McKenzie   protocol   results   in   significant   decrease   in   pain   and   increase   range   of   motion   and   functional   ability   in   spinal conditions   but   there   are   insufficient   data   available   to   determine   the   efficacy   of   the   McKenzie   protocol   on   non   specific   neck   pain   patient’s further   research   which   addresses   these   issues   is   required.   Purpose:   This   study   was   conducted   to   evaluate   the   effect   of   McKenzie   protocol on   cervical   range   of   motion   (CROM),   intensity   of   pain,   and   neck   functional   activity   level   in   the   management   of   non   specific   neck   pain patients. Materials   and   Methods:   Thirty   patients   with   non   specific   neck   pain,30-50   years   of   age      was   assigned      in   two   groups(study   and   control) each   group   contained   fifteen      patients,   all   patients   received   traditional   treatment   for   six   weeks   3times/week   and   additionally   study   group received   McKenzie   protocol.      CROM,   pain,   and   functional   activity   level   were   measured   pre-treatment   and   post   six   weeks   of   treatment using myrin goniometer, visual analog scale (VAS), and Copenhagen neck functional disability scale.  Results:   There   was   a   significant   increase   in   CROM   of   study   group   where   flexion   (p=0.002),   extension   (p=0.0001),   lateral   flexion   (p=0.02) and rotation (p=0.0001), also significant decrees in pain (p=0.0001) and decease in functional disability level (p=0.0001). 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