A     COMPARATIVE     STUDY     BETWEEN     INCIDENCE     OF     CHROMOSOMAL     ABNORMALITIES     IN     SPONTANEOUSLY ABORTED FETAL SAMPLES OF ART AND NON-ART ORIGIN Sayantani Majumdar * 1 , Sreya Moitra 2 , Nidhi Lal 3 . *1,3 Demonstrator, Department of Anatomy, College of Medicine & Sagore Dutta Hospital, Kolkata, West Bengal, India. 2 Assistant Professor, Department of Anatomy, College of Medicine & Sagore Dutta Hospital, Kolkata, West Bengal, India Address   for   correspondence:    Dr.   Sayantani   Majumdar,    Demonstrator,   Department   of   Anatomy,   College   of   Medicine   &   Sagore   Dutta   Hospital,   Kolkata,   West Bengal 700058, India E-Mail: drsayantani727@gmail.com ABSTRACT Objective:   Spontaneous   abortions   are   quite   frequent   among   the   reproductive   age   group   of   our   country.With   the   advent   of   fast   life,infertility   has   become   a major   issue   and   artificial   reproductive   techniques   are   often   the   resort   taken.   This   study   aims   to   throw   some   light   on   the   strength   of   association   of chromosomal abnormalities with artificial reproductive technique. Design   and   participants:    A   cross   sectional   study   was   done   on   50   aborted   fetal   samples   of   both   first   and   second   trimesters   in   a   Government   Medical College,Kolkata. Settings:  The samples were put to collagenase action,cultured and karyotyped to see the incidence of chromosomal abnormality. Main   Outcome   Measures   and   results:      It   was   seen   that   karyotype   abnormality   is   present   in   36.4%   cases   which   applied   ART   in   comparison   to   incidence   of chromosomal abnormality being 43.6% in case of normal pregnancies. Conclusion:    So   it   is   seen   that   Artificial   reproductive   technique   did   not   seem   to   have   strong   association   with   the   incidence   of   chromosomally   abnormal fetus. KEY WORDS:  Artificial reproductive techniques,chromosomal abnormality,aborted fetal samples,karyotyping. References 1 . Manorama Thomas. 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